Electrospinning may sound related to disco music, exercise or pop art. In fact, this is an electrostatic method that can produce nanofibers for items such as layered filters.

The Israeli start-up Nanomedic is using this technology to revolutionize wound care.

Nanomedic's Spincare device—similar to a large nail gun—charges a proprietary polymer from a disposable ampoule and sprays it directly onto the wound as a protective, flexible second skin.

"No matter where the patient is, we can print the electrospun healing fibrous matrix directly on the wound. This has many advantages in promoting the healing process," said Chen Barak, CEO of Nanomedicine, who has a PhD in Biomedical Engineering And years of experience in electrospinning technology.

“You only need to apply it once and there is no need to change the dressing. Patients can take a shower regularly after 24 to 48 hours. When the underlying skin heals, our layers will fall off on their own,” Barak told ISRAEL21c.

Not changing the dressing and not touching the patient means less pain, especially for burn patients. The matrix is ​​used at a distance of about 20 cm (8 inches), regardless of its shape or size, it can completely adhere to any wound.

"Even on the active parts of the face, hands, and body, this is very effective, and unlike many dressings, allows free movement," Barak said.

The electrospun fibers used in Spincare mimic the structure of skin tissue, thereby accelerating healing and reducing scars.

Another big advantage is that healthcare professionals can evaluate the healing process without removing the bandage, because the matrix becomes transparent after use.

Dr. Alexandra Schultz, a plastic surgeon at the German Plastic Surgery and Hand Surgery Clinic Cologne, said that SpinCare “satisfies their individual needs by providing them with maximum mobility and comfort during their rehabilitation. It is very suitable The size and surface of each wound, and can be easily applied by healthcare professionals."

In addition, Schultz said, “This dressing provides an ideal environment for deep wound healing from shallow to partial thickness wounds. In my opinion, Spincare is a modern solution for wound treatment.”

New methods of wound care

Barak explained that nanomedicine devices were first conceptualized by her team about seven years ago. The company was only officially established in 2018.

"Electrospinning machines are large and very complex. In order to use them for wound care, we need to miniaturize this technology, which has never been done before."

Therefore, this unique handheld device can be used not only in hospitals, but also in emergency situations. It can be stored in ambulances and public buildings.

"This is a new innovative wound care product," Barak said. "There are dressings everywhere on the market, but our device is the only one that creates a matrix directly on the wound to cover and protect it during the healing process."

Even severe and complicated wounds only need to be applied once.

Spincare is developed and manufactured in Lod, a suburb of Tel Aviv where Ben Gurion International Airport is located, and was recently launched in Europe.

"We are submitting a proposal to the FDA and hope to list it in the United States in the second half of this year after FDA approval," Barak said.

At the same time, Nanomedic is continuing its clinical trials and recently announced that Spincare will be used in the Rambam Health Care Campus, a 1,000-bed hospital in northern Israel.

"Nanomedic's Spincare system has many advantages, including the ability to prevent bacterial infections and the ability to adhere to damage in an optimal way with conventional dressings," said Professor Yehuda Ullmann, head of the Department of Surgery and Surgery Director of Rambam. Plastic surgery.

"For patients, the biggest benefit is to avoid the pain often caused by changing bandages, especially when treating children."

Barak pointed out that the same platform can be used for multiple purposes, such as aesthetics and cosmetics, dermatology, and surgery.

"We can add additives such as antibacterial agents, collagen or silica gel to the ampoule," she said.

For more information, click here

Abigail Klein Leichman is the writer and associate editor of ISRAEL21c. Before moving to Israel in 2007, she was a professional writer and copy editor for a major daily newspaper in New Jersey, and has been a freelance writer for various newspapers and periodicals since 1984.